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Product Name:Polymyxin B sulfate
CAS No.:1405-20-5
Consistent with USP and EP.
Properties: powder, water solubility: 50mg/mL
White or almost white powder. Almost odourless. Sensitive to light. Hygroscopic. Soluble in water, slightly soluble in ethanol.
Uses: gram negative bacteria, polypeptide antibiotics, can change the membrane structure, so that leakage of small molecules, and inhibit the growth of gram negative bacteria. Bactericidal action against Escherichia coli. The lipid A fraction bound to bacterial lipopolysaccharides. Small holes are induced in the outer membrane of the skin.
Mode of action: binding and interfering permeability of cell plasma membrane. Antimicrobial spectrum: gram negative bacteria.

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